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CAS: 274901-16-5
产品编号: H66251
MDL: MFCD09952339
品牌: INFI
Chemical Name Vildagliptin
CAS Number 274901-16-5
Synonym (2S)-
Chemical Name Translation 维达列汀
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        Packing Group III
      • It is a new oral anti-hyperglycemic agent of a new dipeptidyl peptidase-IV (DPP-IV) inhibitor class of drugs. Antidiabetic.
      • {MCE} [2]. Wu YJ, et al. Dipeptidyl peptidase-4 inhibitor, vildagliptin, inhibits pancreatic beta cell apoptosis in associationwith its effects suppressing endoplasmic reticulum stress in db/db mice. Metabolism. 2015 Feb;64(2):226-35.
      • {TRC} Ahren, B., et al.: Diabetes Care, 27, 2874 (2004),
      • {TRC} Ahren, B., et al.: J. Clin. Endocrinol. Metab., 89, 2078 (2004),
      • {TRC} Barlocco, D., et al.: Curr. Opin. Invest. Drugs, 5, 1094 (2004),
      • {MCE} [1]. Villhauer EB, et al. 1-[[(3-hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine: a potent, selective, and orally bioavailable dipeptidyl peptidase IV inhibitor with antihyperglycemic properties. J Med Chem. 2003 Jun 19;46(13):2774-89.
      • {MCE} [1]. Villhauer EB, et al. 1-[[(3-hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine: a potent, selective, and orally bioavailable dipeptidyl peptidase IV inhibitor with antihyperglycemic properties. J Med Chem. 2003 Jun 19;46(13):2774-89.
      • {MCE} [2]. Wu YJ, et al. Dipeptidyl peptidase-4 in
      • 274901-16-5 H66251 Vildagliptin
维达列汀
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        Mol. Formula C17H25N3O2
        Mol. Weight 303
        Density 1.27
        Boiling Point 531.3

        *以上化合物性质及应用等信息仅供参考